Nanoscale tRNA architecture

July 18th, 2010

US chemists have designed and built self-assembling 3D nanostructures using transfer RNA (tRNA) as a building block. They hope their structures could find uses in areas such as drug delivery.

Luc Jaeger from the University of California at Santa Barbara and his team used the core structure of tRNA to build distorted cube-shaped nanocages. ‘We chose tRNA because it’s a branched structure, shaped like a corner,’ says fellow researcher Cody Geary.

Royal Society of Chemistry